• Stephanie Klinzing, Urs Wenger, Federica Stretti, Peter Steiger, Elisabeth J Rushing, Urs Schwarz, and Marco Maggiorini.
• From the *Surgical Intensive Care Unit and †Medical Intensive Care Unit, University Hospital of Zurich, Zurich, Switzerland; ‡Dipartimento di Fisiopatologia Medico-Chirurgica e dei Trapianti, Università degli Studi di Milano, Milano, Italy; and Departments of §Neuropathology and ‖Neurology, University Hospital of Zurich, Zurich, Switzerland.
• Anesth. Analg. 2017 Nov 1; 125 (5): 1544-1548.

AbstractThis retrospective single-center study investigated the incidence of neurologic injury as determined by autopsy or cerebral imaging in 74 patients undergoing extracorporeal membrane oxygenation (ECMO) for acute respiratory distress syndrome. Seventy-three percent of patients were treated with venovenous and 27% with venoarterial ECMO. ECMO-associated intracerebral hemorrhage was diagnosed in 10.8% of patients. There were no cases of ischemic stroke. Clinical characteristics did not differ between patients with and without neurologic injury. Six-month survival was 13% (Wilson confidence interval, 2%-47%) in patients with severe intracerebral hemorrhage compared to an overall survival rate of 57% (Wilson confidence interval, 45%-67%).

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