• World Neurosurg · Dec 2017

    Revascularization operation for moyamoya disease with concurrent von Willebrand disease: A case report.

    • Kenji Miki, Koichi Arimura, Ataru Nishimura, Koji Yoshimoto, Tetsuro Sayama, and Koji Iihara.
    • Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
    • World Neurosurg. 2017 Dec 1; 108: 991.e17-991.e21.

    BackgroundAlthough extracranial-intracranial (EC-IC) bypass is an effective treatment strategy for symptomatic moyamoya disease, surgeons need to be cautious regarding the possibility of postoperative hemorrhagic complications in patients with a concurrent coagulation disorder. Here, we describe a case of EC-IC bypass for moyamoya disease concurrent with von Willebrand disease type 1.Case DescriptionFollowing perioperative replacement of the von Willebrand factor, the patient showed an uneventful and uncomplicated clinical course.ConclusionThis is the first reported case of EC-IC bypass being performed for moyamoya disease in a patient with concurrent von Willebrand disease. We emphasize the importance of appropriate management with replacement of the von Willebrand factor during the perioperative period to avoid hemorrhagic complications.Copyright © 2017 Elsevier Inc. All rights reserved.

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