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- Keisuke Takai, Shota Tanaka, Takashi Sota, Akitake Mukasa, Takashi Komori, and Makoto Taniguchi.
- Department of Neurosurgery, Tokyo Metropolitan Neurological Hospital, Tokyo, Japan. Electronic address: takai-nsu@umin.ac.jp.
- World Neurosurg. 2017 Dec 1; 108: 991.e13-991.e16.
BackgroundIn 2016, the World Health Organization updated its classification of tumors, adding genetic profiles to the conventional histopathologic typing.Case DescriptionThe authors present herein the first case of a 44-year-old female with isocitrate dehydrogenase-mutant World Health Organization grade II diffuse spinal astrocytoma diagnosed on the basis of both histopathologic and genetic findings.ConclusionsThe present case underscores the significant role of a molecular genetic analysis in the differential diagnosis of intramedullary spinal gliomas.Copyright © 2017 Elsevier Inc. All rights reserved.
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