• Resuscitation · Dec 2017

    End-tidal carbon dioxide and defibrillation success in out-of-hospital cardiac arrest.

    • Simone Savastano, Enrico Baldi, Maurizio Raimondi, Alessandra Palo, Mirko Belliato, Elisa Cacciatore, Valentina Corazza, Simone Molinari, Fabrizio Canevari, Aurora I Danza, Gaetano M De Ferrari, Giorgio Antonio Iotti, and Luigi Oltrona Visconti.
    • Division Of Cardiology, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy. Electronic address: s.savastano@smatteo.pv.it.
    • Resuscitation. 2017 Dec 1; 121: 71-75.

    PurposeBasing on the relationship between the quality of cardiopulmonary resuscitation (CPR) and the responsiveness of VF to the defibrillation we aimed to assess whether the values of ETCO2 in the minute before defibrillation could predict the effectiveness of the shock.Materials And MethodsWe retrospectively evaluated the reports generated by the manual monitor/defibrillator (Corpuls by GS Elektromedizinische Geräte G. Stemple GmbH, Germany) used for cases of VF cardiac arrest from January 2015 to December 2016. The mean ETCO2 value of the minute preceding the shock (METCO260) was computed. A blind evaluation of the effectiveness of each shock was provided by three cardiologists.ResultsA total amount of 207 shocks were delivered for 62 patients. When considering the three tertiles of METCO260 (T1:METCO260 ≤ 20mmHg; T2: 20mmHg < METCO260 ≤ 31mmHg and T3: METCO260 > 31mmHg) a statistically significant difference between the percentages of shock success was found (T1: 50%; T2: 63%; T3: 78%; Chi square p=0.003; p for trend <0.001). When the METCO260 was lower than 7mmHg no shock was effective and when the METCO260 was higher than 45mmHg no shock was ineffective. Shocks followed by ROSC were preceded by higher values of METCO260 as compared either to ineffective shocks or effective ones without ROSC.ConclusionsThis is the first demonstration of the relation between ETCO2 and defibrillation effectiveness. Our findings stress the pivotal role of High Quality CPR, monitored via ETCO2, and suggest ETCO2 monitoring as an additional weapon to guide defibrillation.Copyright © 2017 Elsevier B.V. All rights reserved.

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