• H Furukawa, T Kosuge, K Shimada, J Yamamoto, Y Kanai, K Mukai, R Iwata, and K Ushio.
• Department of Diagnostic Radiology, National Cancer Center Hospital, Tokyo, Japan. hsfuruka@gan2.ncc.go.jp
• Arch Surg Chicago. 1998 Jul 1; 133 (7): 735-9.

ObjectivesTo demonstrate the helical computed tomographic (CT) features of small polypoid lesions of the gallbladder and to establish a clinical strategy based on CT findings for the treatment of such lesions.DesignValidation cohort study.SettingTertiary care public hospital.PatientsThirty-one patients with polypoid lesions of the gallbladder (< or = 3 cm) underwent CT followed by resection.Main Outcome MeasureThe detectability of the lesions on both unenhanced and enhanced CT and the configuration of the lesions on enhanced CT were prospectively evaluated in comparison with the histopathological findings.ResultsUnenhanced CT detected 14 (45%) of the 31 lesions, whereas enhanced CT detected all of the lesions. The detection rates of the neoplastic lesions (adenoma, adenocarcinoma, and metastatic tumor) and cholesterol polyps were 81% (13/16) and 7% (1/15), respectively (P<.001). Among the 20 lesions demonstrated as pedunculated, 6 (30%) were neoplastic, whereas 10 (91%) of the 11 lesions demonstrated as sessile were neoplastic (P<.001). When a lesion was demonstrated on unenhanced CT or its shape was sessile on enhanced CT, the case was diagnosed as a neoplastic lesion. The sensitivity, specificity, positive predictive value, negative predictive value, and overall accuracy of the CT diagnosis of the neoplastic lesions were 88% (14/16), 87% (13/15), 88% (14/16), 87% (13/15), and 87% (27/31), respectively.ConclusionComputed tomography can differentiate neoplastic and nonneoplastic small polypoid lesions of the gallbladder and reliably identify the presence of neoplastic lesions that should be resected.

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