• Enrique Noé, José Olaya, M Dolores Navarro, Paloma Noguera, Carolina Colomer, Javier García-Panach, Sandra Rivero, Belén Moliner, and Joan Ferri.
• Servicio de NeuroRehabilitación y Daño Cerebral de Hospitales NISA y Fundación Hospitales NISA, Valencia, Spain. enoe@comv.es
• Arch Phys Med Rehabil. 2012 Mar 1; 93 (3): 428-33.e12.

ObjectiveTo describe the clinical characteristics and short-term pattern of evolution of a sample of patients within 1 year after acquiring a brain injury that led to a vegetative state (VS) or a minimally conscious state (MCS).DesignCohort study.SettingInpatient brain injury rehabilitation program.ParticipantsPatients with acquired brain injury (N=32; 47% traumatic, 37.5% hemorrhagic, 15.5% anoxic) who were in a VS or an MCS according to Coma Recovery Scale-Revised (CRS-R) scores.InterventionIntegrative multisensory program comprising daily physical rehabilitation procedures and multimodal sensory stimulation.Main Outcome MeasureAll patients were assessed with a Spanish version of the CRS-R at admission and then monthly for at least 6 months or until emergence from MCS.ResultsAt the time of admission, 12 patients were diagnosed as being in a VS and 20 as being in an MCS. Eight patients were able to emerge from their MCS during follow-up. Seven of these 8 patients were diagnosed as being in an MCS at inclusion, and only 1 was diagnosed as being in a VS. Emergence from an MCS was mostly associated with improvement in both the communication and motor function scales (n=4). Lesser chronicity (P=.01) and the presence of more than visual behavioral responses at admission (P=.05) were both significant predictors of emergence from an MCS.ConclusionsThe CRS-R seems appropriate for establishing an immediate prognosis in this population. A quick referral of these patients for specialized assessment and rehabilitation facilities is recommended.Copyright © 2012 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

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