• World Neurosurg · Jan 2018

    Case Reports

    Lymphoblastic lymphoma involving multiple vertebrae.

    • Da Li, Yu-Lun Xu, and Zhen Wu.
    • Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, People's Republic of China.
    • World Neurosurg. 2018 Jan 1; 109: 117-118.

    AbstractAcute lymphoblastic lymphoma is a malignant hematologic disease in childhood but rarely initially involves epidural compartment in adults. A 20-year-old male presented with progressive osphyalgia with constipation. Contrasted magnetic resonance imaging showed multiple vertebrae of hypointense T1 signals and an intraspinal epidural lesion. Subtotal resection was achieved. Histopathology suggested malignant B-cell lymphoma with Ki-67 of 90% and positivity of leukocyte common antigen. A bone marrow biopsy was unequivocally diagnostic of B-cell acute lymphoblastic lymphoma followed by chemotherapy (methotrexate) and partial recovery was observed. The marrow biopsy was necessary if without hypercalcemia and abnormal peripheral blood examination.Copyright © 2017 Elsevier Inc. All rights reserved.

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