• Neuroimaging Clin. N. Am. · Nov 2017

    Review

    Limitations of Resting-State Functional MR Imaging in the Setting of Focal Brain Lesions.

    • Shruti Agarwal, Haris I Sair, and Jay J Pillai.
    • Division of Neuroradiology, The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Phipps B-100, 1800 Orleans Street, Baltimore, MD 21287, USA.... more less
    • Neuroimaging Clin. N. Am. 2017 Nov 1; 27 (4): 645-661.

    AbstractMethods of image acquisition and analysis for resting-state functional MR imaging (rsfMR imaging) are still evolving. Neurovascular uncoupling and susceptibility artifact are important confounds of rsfMR imaging in the setting of focal brain lesions such as brain tumors. This article reviews the detection of these confounds using rsfMR imaging metrics in the setting of focal brain lesions. In the near future, with the wide range of ongoing research in rsfMR imaging, these issues likely will be overcome and will open new windows into brain function and connectivity.Copyright © 2017 Elsevier Inc. All rights reserved.

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