• Am J Emerg Med · Apr 2018

    Is pulseless electrical activity a reason to refuse cardiopulmonary resuscitation with ECMO support?

    • Dirk Pabst and Christoph E Brehm.
    • Heart and Vascular Institute, Penn State Milton S. Hershey Medical Center, Hershey, PA, USA. Electronic address: dpabst@pennstatehealth.psu.edu.
    • Am J Emerg Med. 2018 Apr 1; 36 (4): 637-640.

    BackgroundCardiopulmonary resuscitation with ECMO support (ECPR) has shown to improve outcome in patients after cardiac arrest under resuscitation. Most current recommendations for ECPR do not include patients with a non-shockable rhythm such as PEA and asystole.AimThe aim of this study was to investigate the outcome of 3 patient groups separated by initial rhythm at time of ECMO placement during CPR: asystole, PEA and shockable rhythm.MethodsWe made a retrospective single-center study of adults who underwent ECPR for in-hospital cardiac arrest between June 2008 and January 2017. Outcome and survival were identified in 3 groups of patients regarding to the heart rhythm at the time decision for ECMO support was made: 1. patients with asystole, 2. patients with pulseless electrical activity, 3. patients with a shockable rhythm.Result63 patients underwent ECPR in the mentioned time frame. Five patients were excluded due to incomplete data. Under the 58 included patients the number of cases for asystole, PEA, shockable rhythm was 7, 21 and 30 respectively. The means of CPR-time in these groups were 37, 41 and 37min. Survival to discharge was 0.0%, 23.8% and 40.0% respectively (p=0.09). All survivors to discharge had a good neurological outcome, defined as cerebral performance category 1or 2.ConclusionSurvival to discharge in patients with PEA as initial rhythm at the time of decision for ECPR is 23.8% while no patients with asystole as initial rhythm survived discharge. Patients with PEA should be carefully considered for ECPR.Copyright © 2017 Elsevier Inc. All rights reserved.

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