• Anesthesia and analgesia · Feb 2001

    Case Reports

    The use of lepirudin for anticoagulation in patients with heparin-induced thrombocytopenia during major vascular surgery.

    • Y Sun, P E Greilich, S I Wilson, M R Jackson, and C W Whitten.
    • Department of Anesthesiology & Pain Management, University of Texas Southwestern Medical Center, Dallas, Texas.
    • Anesth. Analg. 2001 Feb 1; 92 (2): 344-6.

    AbstractThe method of anticoagulation in patients undergoing major vascular surgery with a history of heparin-induced thrombocytopenia (HIT) is controversial. We present two cases in which a bolus only technique using recombinant hirudin (Lepirudin or Refludan) was used successfully in patients with HIT scheduled for vascular surgery.

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