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Multicenter Study Observational Study
High rate of isolated right ventricular dysfunction in patients with non-significant computed tomographic pulmonary angiography.
- Frances M Russell, Jeffrey A Kline, and Timothy Lahm.
- Department of Emergency Medicine, Indiana University School of Medicine, United States. Electronic address: framruss@iupui.edu.
- Am J Emerg Med. 2018 Feb 1; 36 (2): 281-284.
BackgroundRight ventricular (RV) dysfunction and pulmonary hypertension (PH) are commonly unrecognized in the emergency department (ED), but are associated with poor outcomes. Prior research has found a 30% prevalence of isolated RV dysfunction in ED patients after non-significant computed tomographic pulmonary angiography (CTPA). We aimed to prospectively define the prevalence of RV dysfunction and/or PH in short of breath ED patients, and assess outcomes.MethodsProspective observational study of patients with a non-significant CTPA. Isolated RV dysfunction and/or PH was defined as normal left ventricular function plus RV dilation, moderate to severe tricuspid regurgitation or RV systolic pressure>40mmHg on comprehensive echocardiography.ResultsOf 83 patients, 20 (24%, 95% [confidence interval] CI: 16-34%) had isolated RV dysfunction and/or PH. These patients had 40% ED recidivism and 30% hospital readmission at 30-days. When compared to patients with normal echocardiographic function, they had significantly longer intensive care unit and hospital length of stays.ConclusionsIn a prospective cohort of ED patients, we found a high prevalence of isolated RV dysfunction and/or PH after a non-significant CTPA. These patients had high rates of recidivism and hospital readmission. This data supports a continued need for ED based screening and specialty referral.Copyright © 2017 Elsevier Inc. All rights reserved.
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