• Minghui Zheng, Wei Ji, Lin Zou, Zhiping Huang, Qingan Zhu, and Dongbin Qu.
• Department of Spinal Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
• World Neurosurg. 2018 Feb 1; 110: e459-e464.

ObjectiveTo evaluate stability of anterior transdiscal axial screw (ATAS) fixation for anterior instrumentation and to compare with standard anterior cervical decompression and fusion and plate (ACDFP) fixation in human subaxial cervical spine.MethodsFlexibility tests were conducted on 7 cadaveric specimens (C5-T1) in an intact and injured state and instrumented with ACDFP fixation, ATAS fixation, and ACDFP plus ATAS fixation at the C6-7 segment after section of the anterior and posterior longitudinal ligaments and discectomy. A pure moment of ±2.0 N-m was applied to the specimen in flexion-extension, lateral bending, and axial rotation. Range of motion (ROM) and neutral zone were calculated for the C6-7 segment.ResultsROM was reduced significantly compared with the intact or injured condition for 3 configurations under all motions. ATAS fixation resulted in similar ROM in C6-7 compared with ACDFP fixation in flexion (2.7° vs. 2.6°, P = 0.419), extension (2.7° vs. 2.1°, P = 0.152), and lateral bending (4.6° vs. 4.2°, P = 0.295) but larger ROM in axial rotation (6.1° vs. 5.3°, P = 0.014). When combined with an anterior plate, ATAS fixation reduced ROM to 1.2° in flexion, 1.1° in extension, 3.3° in lateral bending, and 3.8° in axial rotation, which were significantly smaller than ACDFP or ATAS fixation alone.ConclusionsATAS fixation is a biomechanically effective alternative or supplemental method of anterior fixation in subaxial cervical spine.Copyright © 2017 Elsevier Inc. All rights reserved.

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