• World Neurosurg · Feb 2018

    Comparative Study

    Usefulness of FDG-PET in comparison with methionine-PET in differentiating solid hemangioblastoma from adult cerebellar tumors.

    • Yoshinobu Takahashi, Akimasa Nishio, Daisuke Yamamoto, Hajime Kamada, and Naoya Hashimoto.
    • Department of Neurosurgery, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan. Electronic address: t-ysnb@koto.kpu-m.ac.jp.
    • World Neurosurg. 2018 Feb 1; 110: e648-e652.

    Background And PurposeAmong adults with posterior fossa tumors, an intraaxial location of the tumor is less common than an extraaxial location. Moreover, the differential diagnosis of a single cerebellar tumor in adults is sometimes difficult by conventional magnetic resonance imaging. We aimed to report the findings of positron emission tomography (PET) using 18F-fluorodeoxyglucose (FDG) and methionine in adult patients with intraaxial and solitary metastatic brain tumors.Materials And MethodsFDG-PET was performed on 12 patients with posterior fossa tumors: 4 had solid hemangioblastoma (HB), 3 had primary central nervous system lymphomas, 1 had a glioblastoma, and 4 had single metastatic brain tumors (METs). Methionine-PET was performed on 9 patients except for 1 patient with a MET. The maximum standardized uptake value (SUVmax) of the tumor was measured and compared with pathologic findings.ResultsThe SUVmax of FDG in HB was lower compared with that of other tumors (P = 0.001). On the other hand, the SUVmax of methionine in the HB cases was almost the same as that in other tumors (P = 0.07).ConclusionFDG-PET was helpful in differentiating HBs from adult cerebellar tumors.Copyright © 2017 Elsevier Inc. All rights reserved.

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