• Vector Borne Zoonotic Dis. · Oct 2017

    Genomic Characterization of Crimean-Congo Hemorrhagic Fever Virus in Hyalomma Tick from Spain, 2014.

    • Maria N B Cajimat, Sergio E Rodriguez, Isolde U E Schuster, Daniele M Swetnam, Thomas G Ksiazek, Miguel A Habela, Ana Isabel Negredo, and Agustín Estrada-Peña.
    • 1 Galveston National Laboratory, Department of Microbiology & Immunology, Institute for Human Infections and Immunity, University of Texas Medical Branch , Galveston, Texas.
    • Vector Borne Zoonotic Dis. 2017 Oct 1; 17 (10): 714-719.

    AbstractCrimean-Congo hemorrhagic fever (CCHF) is a severe tick-borne disease caused by CCHF virus (CCHFV). Ticks in the genus Hyalomma are the main vectors and reservoirs of CCHFV. In Spain, CCHFV was first detected in Hyalomma ticks from Cáceres in 2010. Subsequently, two autochthonous CCHF cases were reported in August 2016. In this study, we describe the characterization of the CCHFV genome directly from Hyalomma lusitanicum collected in Cáceres in 2014. Phylogenetic analyses reveal a close relationship with clade III strains from West Africa, with an estimated divergence time of 50 years. The results of this work suggest that CCHFV has been circulating in Spain for some time, and most likely originated from West Africa.

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