• West J Emerg Med · Mar 2016

    Case Reports

    Salicylate Toxicity from Genital Exposure to a Methylsalicylate-Containing Rubefacient.

    • Trevonne M Thompson, Theodore Toerne, and Timothy B Erickson.
    • The University of Illinois at Chicago, Department of Emergency Medicine, Chicago, Illinois.
    • West J Emerg Med. 2016 Mar 1; 17 (2): 181-3.

    AbstractMethylsalicylate-containing rubefacients have been reported to cause salicylate poisoning after ingestion, topical application to abnormal skin, and inappropriate topical application to normal skin. Many over-the-counter products contain methylsalicylate. Topical salicylates rarely produce systemic toxicity when used appropriately; however, methylsaliclyate can be absorbed through intact skin. Scrotal skin can have up to 40-fold greater absorption compared to other dermal regions. We report a unique case of salicylate poisoning resulting from the use of a methylsalicylate-containing rubefacient to facilitate masturbation in a male teenager. Saliclyate toxicity has not previously been reported from the genital exposure to methylsaliclyate.

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