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- Jack Louro, Katherine Andersen, and Roman Dudaryk.
- From the *Department of Clinical Anesthesiology, University of Miami, Miami, Florida; and †Anesthesiology Resident, University of Miami, Jackson Memorial Hospital, Miami, Florida.
- A A Case Rep. 2017 Sep 1; 9 (5): 144-147.
AbstractCoagulopathy induced by trauma or cirrhosis is a well-recognized entity. Viscoelastic testing has been used in either condition for goal-directed transfusion and detection of fibrinolysis since conventional coagulation tests do not correlate with clinical risk of bleeding. Hemostatic resuscitation may not be adequate for a trauma patient with liver disease due to complex alterations in coagulation systems and occasionally require adjuvant therapy. We report a case of trauma-induced coagulopathy presenting as severe hyperfibrinolysis in a cirrhotic patient who was refractory to hemostatic resuscitation but was rapidly corrected by the administration of tranexamic acid and recombinant Factor VIIa.
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