• Rheum. Dis. Clin. North Am. · May 2015

    Review

    Management of connective tissue disease-associated interstitial lung disease.

    • Sandra Chartrand and Aryeh Fischer.
    • Department of Medicine, National Jewish Health, University of Colorado School of Medicine, 1400 Jackson Street, Denver, CO 80206, USA; Department of Medicine, Rheumatology Clinic, Hôpital Maisonneuve-Rosemont, Université de Montréal, 5415 Boulevard de l'Assomption, Montréal, Québec H1T 2M4, Canada.
    • Rheum. Dis. Clin. North Am. 2015 May 1; 41 (2): 279-94.

    AbstractA thorough, often multidisciplinary assessment to determine extrathoracic versus intrathoracic disease activity and degrees of impairment is needed to optimize the management of connective tissue disease (CTD)-associated interstitial lung disease (ILD). Pharmacologic intervention with immunosuppression is the mainstay of therapy for all forms of CTD-ILD, but should be reserved for those that show clinically significant and/or progressive disease. The management of CTD-ILD is not yet evidence based and there is a need for controlled trials across the spectrum of CTD-ILD. Nonpharmacologic management strategies and addressing comorbidities or aggravating factors should be included in the comprehensive treatment plan for CTD-ILD. Copyright © 2015 Elsevier Inc. All rights reserved.

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