• Anesthesia and analgesia · Sep 2019

    Point-of-Care Fibrinogen Testing in Pregnancy.

    • Daniel Katz, Joshua Hamburger, Dorian Batt, Jeffrey Zahn, and Yaakov Beilin.
    • From the Department of Anesthesiology, Pain, and Perioperative Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.
    • Anesth. Analg. 2019 Sep 1; 129 (3): e86e88e86-e88.

    AbstractAgreement between estimated fibrinogen concentration via thromboelastography and traditional assays is not established in the parturient. We therefore recruited 56 parturients and performed Clauss and functional fibrinogen level (FLEV) tests. Mean difference of measurements was 36.8 mg/dL (95% CI, 21.8-51.9) with a standard deviation of 52.8 mg/dL. Calculated limits of agreement were 140.2 mg/dL (95% CI, 166.3-114.6) and -66.6 mg/dL (95% CI, -40.8 to -92.5), within the maximum allowable difference of 165 mg/dL. We therefore conclude that while most measurements fell within the limits of agreement, more work is needed to clearly define the role of this test in the obstetric population.

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