• Jacob J Strand, Lindsay L Warner, Mihir M Kamdar, Alice W Flaherty, and Vicki A Jackson.
• 1 Division of General Internal Medicine, Center for Palliative Medicine , Mayo Clinic, Rochester, Minnesota.
• J Palliat Med. 2018 Feb 1; 21 (2): 266-268.

AbstractCentral pain syndromes are a complex, diverse group of clinical conditions that are poorly understood. We present a patient with progressive, debilitating central pain and co-existing mood disorders that was refractory to multimodal pharmacologic and nonpharmacologic therapies, but that ultimately responded to electroconvulsive therapy (ECT). The patient described it at various times as her skin being "lit on fire," "stabbed," "squeezed like a boa constrictor," or itching unbearably. She underwent a course of three sequential ECT treatments during her hospitalization and it dramatically decreased her pain. She began maintenance ECT, and a rate of roughly one treatment a month provided persistent pain suppression. Despite this lack of evidence, ECT has a favorable safety profile and can be considered in the therapeutic armamentarium for patients who have exhausted standard treatment regimens who continue to have suffering in the setting of central pain syndromes and coexisting mood disorders.

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