• Maki Nagamatsu, Taeko Takagi, Tadatomo Ohyanagi, Satoshi Yamazaki, Sachihiko Nobuoka, Hiromu Takemura, Hironobu Akita, Mitsuo Miyai, and Kiyofumi Ohkusu.
• Department of Clinical Laboratory, St. Marianna University School of Medicine, 2-16-1 Sugao, Miyamae-ku, Kawasaki, Kanagawa 216-8511, Japan. m-naga.7122@marianna-u.ac.jp
• J. Infect. Chemother. 2012 Apr 1; 18 (2): 265-8.

AbstractWe encountered a case of neonatal meningitis caused by Streptococcus gallolyticus subsp. pasteurianus. The patient was an 8-day-old boy. Gram staining of the cerebrospinal fluid (CSF) revealed gram-positive cocci in pairs or in short chains. In culture, γ-streptococcus-like colonies grew. The result of 16S rRNA sequence analysis identified S. gallolyticus subsp. pasteurianus. From these results, bacterial meningitis was diagnosed and, as a result of antimicrobial susceptibility testing, single-dose ampicillin therapy was given. Because inflammatory deterioration and spread was suspected from the CSF test results, this therapy was added by panipenem/betamipron. In response to his recovery, antibiotic treatment was stopped and the boy was discharged. This bacterium was classified as S. gallolyticus subsp. pasteurianus in the latest report in 2003. Since this change, there have only been a few cases of neonatal meningitis caused by this bacterium. Here we report this rare case.

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