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- Michael Ruf, Dieter Stoltze, Harry R Merk, Michael Ames, and Jürgen Harms.
- Department of Orthopedics and Traumatology, Zentralklinikum Suhl, Suhl, Germany. michael.ruf@zs.srh.de
- Spine. 2007 Apr 20; 32 (9): E275-80.
Study DesignA retrospective clinical and radiologic evaluation of patients with vertebral osteomyelitis treated via radical debridement and stabilization using titanium mesh cages.ObjectiveTo assess the efficacy of titanium mesh cages in the treatment of active vertebral osteomyelitis.Summary Of Background DataAlthough titanium mesh cages have proven to be superior in trauma and tumor reconstructions, there are few reports regarding the use of titanium mesh cages in the presence of active pyogenic or tuberculotic vertebral osteomyelitis.MethodsA total of 88 cases with vertebral osteomyelitis were operated on between January 2000 and December 2002. There were 2 craniocervical, 13 cervical, 19 thoracic, 11 thoracolumbar, and 43 lumbar infections. The titanium mesh cages replaced 1 disc in 34 cases, 1 vertebral body in 28 cases, 2 vertebral bodies in 23 cases, and 3 vertebral bodies in 3 cases.ResultsAll patients showed a solid bony fusion without any recurrence of infection at latest follow-up. Changes in pain score, Frankel's classification, and blood parameters demonstrated a significant clinical improvement in all patients. The sagittal profile was restored.ConclusionsThe use of titanium mesh cages in the treatment of vertebral osteomyelitis effectively reconstructs the anterior column, while adding stability and restoring the sagittal profile. There is no increase in the rate of recurrence or persistence of infection related to the implantation of titanium mesh cages.
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