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Asia Pacific allergy · Oct 2013
ReviewRecent applications of basophil activation tests in the diagnosis of drug hypersensitivity.
- Woo-Jung Song and Yoon-Seok Chang.
- Department of Internal Medicine, Seoul National University College of Medicine, Seoul 100-799, Korea. ; Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul 100-799, Korea.
- Asia Pac Allergy. 2013 Oct 1; 3 (4): 266-80.
AbstractImmediate-type drug hypersensitivity is an increasingly significant clinical issue; however, the diagnosis is frequently hindered due to lack of safe and precise diagnostic tests. Flow cytometry-assisted basophil activation test is a safe in vitro diagnostic tool for assessing basophil activation upon allergen stimulation. In this review, we have summarized current literature on the diagnostic utilities, new indications, and methodological aspects of the basophil activation test for the diagnosis of drug hypersensitivity.
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