• J. Neurol. Sci. · Jul 2004

    Case Reports

    HTLV-I associated myelopathy/tropical spastic paraparesis in a 7-year-old boy associated with infective dermatitis.

    • Maria de Fátima S P de Oliveira, Achiléa L Bittencourt, Carlos Brites, George Soares, Carrijo Hermes, and Fabrício Oliveira Almeida.
    • Department of Internal Medicine, School of Medicine, Federal University of Bahia (UFBA), Brazil. fatimaoliv@bol.com.br
    • J. Neurol. Sci. 2004 Jul 15; 222 (1-2): 35-8.

    AbstractHTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic myelopathy characterized by a slowly progressive spastic paraparesis and sphincter disturbances beginning in adulthood. Only eight well-documented cases occurring in childhood and adolescence have been described. Infective dermatitis associated to the HTLV-I (IDH) is a chronic eczema of childhood occurring in vertically infected carriers. Here we describe a 7-year-old boy with HAM/TSP and IDH. The neurological manifestations were spastic gait, hyperreflexia of lower limbs, clonus and bilateral Babinski's sign. High levels of HTLV-I antibodies in the serum and in the cerebrospinal fluid were observed. The association of these two diseases and the early onset of HAM/TSP are probably related to a strong humoral anti-HTLV-I response.

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