• Bolni Marius Nagalo, Cyrille Bisseye, Mahamoudou Sanou, Kisito Kienou, Yacouba K Nebié, Alice Kiba, Honorine Dahourou, Siaka Ouattara, Jean Baptiste Nikiema, Rémy Moret, Jean Didier Zongo, and Jacques Simpore.
• Centre National de Transfusion Sanguine, Ouagadougou, Burkina Faso  Centre de Recherche Biomoléculaire Pietro Annigoni, Ouagadougou, Burkina Faso.
• Trop. Med. Int. Health. 2012 Feb 1; 17 (2): 247-53.

Background And ObjectiveThe high prevalence of numerous transfusion-transmitted infectious diseases such as HIV, HBV, HCV and syphilis in sub-Saharan Africa affects blood safety for transfusion recipients. The aim of this study was to evaluate the prevalence and incidence of transfusion-transmissible infectious diseases among blood donors in Burkina Faso.MethodsA retrospective study of blood donors' records from January to December 2009 was conducted. Prevalence and incidence of viral infections were calculated among repeat and first-time blood donors.ResultsOf the total of 31405 first-time volunteer blood donors in 2009, 24.0% were infected with at least one pathogen and 1.8% had serological evidence of multiple infections. The seroprevalence of HIV, HBV, HCV and syphilis in first-time volunteer donors was 1.8%, 13.4%, 6.3% and 2.1%, respectively. In 3981 repeat donors, the incidence rate was 3270.2, 5874.1 and 6784.6 per 100000 donations for anti-HIV-1, HBsAg and anti-HCV, respectively. These numbers varied significantly according to populations where blood is collected and blood centres in Burkina Faso.ConclusionThe relatively high prevalence of viral markers in first-time volunteers and remarkably high incidence of infections in repeat donors raise concerns regarding the safety of these donors and suggest that implementation of NAT might significantly improve the situation.© 2011 Blackwell Publishing Ltd.

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