• Can J Emerg Med · Oct 2018

    Case Reports

    Intentional overdose of liraglutide in a non-diabetic patient causing severe hypoglycemia.

    • Kevin J Solverson, Holly Lee, and Christopher J Doig.
    • *Department of Critical Care Medicine,Cumming School of Medicine,University of Calgary,Calgary,AB.
    • Can J Emerg Med. 2018 Oct 1; 20 (S2): S61-S63.

    AbstractABSTRACTCases of liraglutide overdose are rare in the literature. Prior reports have not found hypoglycemia related to the medication overdose. We describe a case of a non-diabetic patient who intentionally overdosed on liraglutide leading to severe hypoglycemia. The patient required admission to the intensive care unit for a dextrose infusion and close monitoring. Glucagon-like protein-1 agonists are recognized for their safety and rarely causing hypoglycemia in diabetic patients. However, in this case the patient's non-diabetic status may have put him at risk for hypoglycemia in contrast to prior cases showing no hypoglycemia in diabetic patients. The case highlights the possible dangers of liraglutide overdose and need for blood glucose monitoring in the acute presentation.

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