• Lancet · Aug 1980

    Case Reports

    Treatment of acute respiratory failure with low-frequency positive-pressure ventilation and extracorporeal removal of CO2.

    • L Gattinoni, A Agostoni, A Pesenti, A Pelizzola, G P Rossi, M Langer, S Vesconi, L Uziel, U Fox, F Longoni, T Kolobow, and G Damia.
    • Lancet. 1980 Aug 9; 2 (8189): 292-4.

    AbstractTerminal respiratory failure was reversed in three patients with a combination of extra-corporeal CO2 removal through a membrane lung and oxygen diffusion into the diseased lungs between mechanical breaths induced at a frequency of 2-3/min. The technique seems to prevent the pulmonary barotrauma and extrapulmonary derangements caused by conventional mechanical ventilation.

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