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J Stroke Cerebrovasc Dis · Mar 2018
Multicenter Study Comparative StudyDerivation and Validation of the Emergency Medical Stroke Assessment and Comparison of Large Vessel Occlusion Scales.
- Toby I Gropen, Amelia Boehme, Sheryl Martin-Schild, Karen Albright, Alyana Samai, Sammy Pishanidar, Nazli Janjua, Ethan S Brandler, and Steven R Levine.
- Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama. Electronic address: tgropen@uabmc.edu.
- J Stroke Cerebrovasc Dis. 2018 Mar 1; 27 (3): 806-815.
BackgroundThis study aims to develop a simple scale to identify patients with prehospital stroke with large vessel occlusion (LVO), without losing sensitivity for other stroke types.MethodsThe Emergency Medical Stroke Assessment (EMSA) was derived from the National Institutes of Health Stroke Scale (NIHSS) items and validated for prediction of LVO in a separate cohort. We compared the EMSA with the 3-item stroke scale (3I-SS), Cincinnati Prehospital Stroke Severity Scale (C-STAT), Rapid Arterial oCclusion Evaluation (RACE) scale, and Field Assessment Stroke Triage for Emergency Destination (FAST-ED) for prediction of LVO and stroke. We surveyed paramedics to assess ease of use and interpretation of scales.ResultsThe combination of gaze preference, facial asymmetry, asymmetrical arm and leg drift, and abnormal speech or language yielded the EMSA. An EMSA less than 3, 75% sensitivity, and 50% specificity significantly reduced the likelihood of LVO (LR- = .489, 95% confidence interval .366-0.637) versus 3I-SS less than 4 (.866, .798-0.926). A normal EMSA, 93% sensitivity, and 47% specificity significantly reduced the likelihood of stroke (LR- = .142, .068-0.299) versus 3I-SS (.476, .330-0.688) and C-STAT (.858, .717-1.028). EMSA was rated easy to perform by 72% (13 of 18) of paramedics versus 67% (12 of 18) for FAST-ED and 6% (1 of 18) for RACE (χ2 = 27.25, P < .0001), and easy to interpret by 94% (17 of 18) versus 56% (10 of 18) for FAST-ED and 11% (2 of 18) for RACE (χ2 = 21.13, P < .0001).ConclusionsThe EMSA has superior abilities to identify LVO versus 3I-SS and stroke versus 3I-SS and C-STAT. The EMSA has similar ability to triage patients with stroke compared with the FAST-ED and RACE, but is simpler to perform and interpret.Copyright © 2018 National Stroke Association. Published by Elsevier Inc. All rights reserved.
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