• Rubén Roy, Elisabet Sánchez-Rodríguez, Santiago Galán, Mélanie Racine, Elena Castarlenas, Mark P Jensen, and Jordi Miró.
• Department of Psychology, Universitat Rovira i Virgili, Unit for the Study and Treatment of Pain - ALGOS, Research Center for Behavior Assessment (CRAMC), Catalonia, Spain.
• Pain Med. 2019 Mar 1; 20 (3): 555-563.

ObjectiveTo identify the modifiable and nonmodifiable variables that are associated with and might moderate the presence of migraine in the general population.DesignNationally representative cross-sectional survey.SettingNoninstitutionalized population of Spain.SubjectsIndividuals aged 15 years or older (N = 22,842).MethodsA secondary analysis of data from the second wave of the European Health Interview Survey conducted in Spain (2014/2015). We estimated the prevalence of migraine and its distribution according to the study variables, and then built a multivariate logistic model encompassing age, sex, depression severity, chronic anxiety, body mass index, physical activity, smoking status, alcohol use, and perceived social support to predict migraine.ResultsThe one-year prevalence of migraine was 8%. The final multivariate model (Wald χ2 = 693.00, df = 15, P < 0.001) retained depression severity, chronic anxiety, exercising several times a month or week, and alcohol use as predictors of migraine (odds ratios = 2.1-3.5 for positive associations, odds ratios = 0.4-0.9 for negative associations).ConclusionsRaising awareness among clinicians regarding the fact that many of the variables that potentially contribute to the presence of migraine are modifiable (e.g., psychological problems and lifestyle behaviors) might intensify resources dedicated to assessing and impacting these factors in order to potentially prevent the frequency and severity of migraine.© 2018 American Academy of Pain Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

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