• Laryngo- rhino- otologie · Dec 2001

    [Oromandibular dystonia. Clinical forms, diagnosis and examples of therapy with botulinum toxin].

    • R Laskawi and S Rohrbach.
    • Universitäts-Hals-Nasen-Ohren-Klinik Göttingen, Germany. rlaskawi@med.uni-goettingen.de
    • Laryngorhinootologie. 2001 Dec 1; 80 (12): 708-13.

    BackgroundThe present study reports on our experience with clinical aspects and therapy of oromandibular dystonia (OMD) with botulinum toxin A. OMD is a very rare form of focal dystonias. The clinical symptoms can vary considerably, depending on the musculature affected.PatientsThe various clinical forms are described. The description of the diagnostic analysis and the therapy with botulinum toxin A is explained with reference to the patients. In these cases, injections are made into the musculature of the base of the mouth, the muscles involved in chewing, the extrinsic muscles of the tongue and the caudal facial musculature.ResultsMost of the patients showed an improvement of their symptoms. The average dose of Botox(R) used was 35.4+/-23.6 units. The duration of the effect was 14+/-9.2 weeks on average.ConclusionThe therapy for OMD using botulinum toxin A has proved to be successful, the amount of improvement in this form of dystonia is, however, lower in comparison to other forms of mobility disorders in the head and neck region.

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