• Clinical calcium · Dec 2009

    Review

    [Application of FRAX for health check-ups].

    • Saeko Fujiwara.
    • Department of Clinical Studies, Radiation Effects Research Foundation, Japan.
    • Clin Calcium. 2009 Dec 1; 19 (12): 1730-4.

    AbstractWHO's FRAX aims to identify bone-fracture high-risk individuals requiring medical intervention by calculating each individual's 10-year probability (%) of bone fracture based on clinical risk factors or clinical risk factors plus bone mineral density (BMD). The risk factors are age, sex, femoral neck mineral density, or body mass index (BMI) if BMD data are unavailable, history of bone fracture, parental history of femoral neck fracture, smoking, consumption of alcohol, use of steroids, rheumatoid arthritis, and secondary osteoporosis. Model with clinical risk factors alone can predict osteoporotic fracture risk as well as the model with BMD and clinical risk factors. FRAX with clinical risk factors alone would be useful to screen those at high risk of fracture in population-based health check-ups.

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