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- Sarah K Wilcox, Anne Garry, and Miriam J Johnson.
- Palliative Care Team Office, Cancer Care Centre, York Hospital, York, UK. sarahdoc_2000@yahoo.com.au
- J Pain Symptom Manage. 2009 Sep 1; 38 (3): 460-5.
AbstractPersistent hiccups may have a considerable impact on general health through disturbance of diet, sleep, and mood. They can cause exhaustion, malnutrition, dehydration, wound dehiscence, and even death in extreme cases. We report a complex clinical case of intractable hiccups in a patient with cancer of the pancreas and Parkinson's disease and some of the problems encountered when attempting symptom control. We also discuss a potential therapeutic response to a novel agent, amantadine, unlicensed in the treatment of hiccups.
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