• Medwave · Sep 2017

    Case Reports

    Pulmonary alveolar proteinosis: a case report.

    • Luis Alberto Concepción-Urteaga, Luis Alejandro Rodríguez-Hidalgo, Jorge Luis Cornejo-Portella, Oscar Neri Alquizar-Horna, Daniel Anderson Aguilar-Villanueva, Marcio José Concepción-Zavaleta, and Mario Gustavo Azañero-Luján.
    • Centro de Excelencia para el manejo de Tuberculosis “Luz Caviedes Rojas”, Hospital Regional Docente de Trujillo, Trujillo, Perú; Facultad de Medicina, Universidad Nacional de Trujillo, Trujillo, Perú. Address: Avenida Huamán 242, Víctor Larco, Trujillo, Perú. Email: luisconcepcionurteaga@hotmail.com.
    • Medwave. 2017 Sep 14; 17 (8): e7040.

    IntroductionPulmonary alveolar proteinosis is a rare, diffuse interstitial lung disease, characterized by alveolar obstruction due to the accumulation of pulmonary surfactant.Clinical PresentationA 30-year-old male with progressively worsening dyspnea and non-productive cough for one year. He was a sugar cane plantation worker and had prior recurrent respiratory infections. Physical exam revealed cyanosis, and bilateral coarse and fine rales. Chest computed tomography showed diffuse crazy paving pattern. Bronchoscopy with bronchoalveolar lavage yielded a foamy, thick whitish material. Cytology revealed lymphocytes and acellular proteinaceous eosinophilic material. Transbronchial biopsy confirmed the diagnosis of pulmonary alveolar proteinosis. Patient met criteria for whole lung lavage, responding favorably to this therapy.ConclusionPulmonary alveolar proteinosis is a rare lung disease and important to consider due to the diagnostic and therapeutic challenge it represents.

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