• Médecine sciences : M/S · Nov 2017

    [CAR-T immunotherapy, a regulatory milestone].

    • Bertrand Jordan.
    • UMR 7268 ADÉS, Aix-Marseille, Université/EFS/CNRS, Espace éthique méditerranéen, hôpital d'adultes la Timone, 264, rue Saint-Pierre, 13385 Marseille Cedex 05, France ; CoReBio PACA, case 901, parc scientifique de Luminy, 13288 Marseille Cedex 09, France.
    • Med Sci (Paris). 2017 Nov 1; 33 (11): 1003-1006.

    AbstractThe first therapy based on chimeric antigen receptors has been approved by the FDA. It gives excellent results in recurrent paediatric ALL; its cost is very high but fairly consistent with the clinical benefit (long term remission approaching a cure). In spite of their complexity and cost, CAR-T therapies will probably end up playing a very significant role in cancer therapy.© 2017 médecine/sciences – Inserm.

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