• Seokchun Lim, Louanne M Carabini, Robert B Kim, Ryan Khanna, Nader S Dahdaleh, and Zachary A Smith.
• Department of Neurological Surgery, Henry Ford Hospital, 2799 W Grand Blvd, Detroit, MI 48208, USA.
• Spine J. 2017 Mar 1; 17 (3): 313-320.

Background ContextHigher American Society of Anesthesiologists (ASA) classification is a known predictor of postoperative complication in diverse surgical settings. However, its predictive value is not established in single-level elective anterior cervical discectomy and fusion (SLE-ACDF).PurposeThis study aimed to evaluate the predictive value of ASA classification system on 30-day morbidity following SLE-ACDF.Design/SettingPatients who underwent SLE-ACDF between 2011 and 2013 were selected from the American College of Surgeons National Surgical Quality Improvement Program database.Patient SampleA total of 6,148 patients were selected from the 2011-2013 American College of Surgeons National Surgical Quality Improvement Program database.Outcome MeasuresAll outcomes are self-report measures as tracked by dedicated clinical reviewers via prospective review of inpatient charts, outpatient clinic visits, and direct contact with the surgical team.MethodsPropensity score matching and multiple logistic regression analyses were performed to evaluate ASA classification as 30-day morbidity predictor. This study has no financial conflict and has no potential conflict of interest to disclose.ResultsA total of 6,148 patients were analyzed in this study. Patients in the ASA >II cohort had higher incidence of comorbidities and postoperative complications (overall complication, pneumonia, unplanned intubation, ventilator dependent >48 hours, cerebrovascular accident or stroke, catastrophic outcome, and airway complication). Propensity score matching yielded 1,628 pairs of well-matched patients. Multivariable analyses with the propensity score matched dataset revealed the following associations between ASA class >II and 30-day outcomes: any complication (odds ratio [OR] 0.82, 95% confidence interval [CI] 0.48-1.41), pneumonia (OR 1.22, 95% CI 0.33-4.56), unplanned intubation (OR 1.49, 95% CI 0.41-5.36), ventilator >48 hours (OR 5.92, 95% CI 0.69-50.96), catastrophic outcome (OR 1.02, 95% CI 0.39-2.71), and airway complication (OR 2.21, 95% CI 0.67-7.29).ConclusionsAlthough we did not detect associations between ASA class >II and adverse 30-day outcomes following SLE-ACDF, imprecision of estimates precludes definitive inferences. Although ASA classification allows simple assessment of patients' physiological status, their overall perioperativerisk factors need to be considered collectively for adequate optimization and improved outcomes in SLE-ACDF.Copyright © 2016 Elsevier Inc. All rights reserved.

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