• Dania M Rumbak and Wenzhu Mowrey.
• Division of Pediatric Critical Care Medicine, Department of Pediatrics, Children's Hospital at Montefiore/Albert Einstein College of Medicine, USA Division of Child and Adolescent Health, Department of Pediatrics, Columbia University Medical Center, New York, NY, USA daniarumbak@gmail.com.
• J. Child Neurol. 2016 Feb 1; 31 (2): 153-8.

AbstractOur objective was to characterize our experience with 8 patients with Rett syndrome undergoing scoliosis surgery in regard to rates of respiratory failure and rates of ventilator-acquired pneumonia in comparison to patients with neurologic scoliosis and adolescent idiopathic scoliosis. This study was a retrospective chart review of patients undergoing scoliosis surgery at a tertiary children's hospital. Patients were divided into 3 groups: (1) adolescent idiopathic scoliosis, (2) neurologic scoliosis, and (3) Rett syndrome. There were 133 patients with adolescent idiopathic scoliosis, 48 patients with neurologic scoliosis, and 8 patients with Rett syndrome. We found that patients with Rett syndrome undergoing scoliosis surgery have higher rates of respiratory failure and longer ventilation times in the postoperative period when compared with both adolescent idiopathic scoliosis and neurologic scoliosis patients. There is insufficient evidence to suggest a difference in the incidence of ventilator-acquired pneumonia between the Rett syndrome and the neurologic scoliosis group. We believe our findings are the first in the literature to show a statistically significant difference between these 3 groups in regard to incidence of respiratory failure. © The Author(s) 2015.

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