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- R J Roberge and E P Krenzelok.
- Department of Emergency Medicine, St Francis Medical Center, Pittsburgh, PA 15201, USA.
- Vet Hum Toxicol. 2001 Feb 1; 43 (1): 42-4.
AbstractSevere tricyclic antidepressant (TCA) overdose is generally manifested by cardiovascular and/or central nervous system toxicity. Although the majority of patients who are comatose following these overdoses regain consciousness within 24 h, this case had 5-days of coma with associated loss of brainstem reflexes. Severe central nervous system depression can occur as a sole manifestation of TCA overdose without concomitant cardiovascular toxicity.
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