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- Irene García-Morales, Amalia Pérez-Gil, and Francisco M Camacho.
- Departamento de Dermatología, Hospital Universitario Virgen Macarena, Sevilla. España. irenegm@supercable.es
- Actas Dermosifiliogr. 2006 Oct 1; 97 (8): 529-32.
AbstractThe term Marjolin's ulcer means the malignant transformation of chronic ulcers, sinus tract and burn scars. The most frequently produced neoplasm is squamous cell carcinoma. The pathogeny is unknown, involving mutations in the Fas gene. Main therapeutic management are consist of prophylactic measures, avoiding repeated traumas and prolonged cure periods. We present the case of a 48-year-old male with squamous cell carcinoma on the old burn scar of legs that evolved favorably after excision.
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