• J. Gastrointest. Surg. · Jun 2017

    Randomized Controlled Trial

    Effect of Adding Dexmedetomidine to Ropivacaine on Ultrasound-Guided Dual Transversus Abdominis Plane Block after Gastrectomy.

    • Wengang Ding, Wanying Li, Xianzhang Zeng, Jinying Li, Jingjing Jiang, Changchun Guo, and Wenzhi Li.
    • Department of Anesthesiology, The Second Affiliated Hospital of Harbin Medical University, 246, Xuefu Road, Harbin, Heilongjiang, 150086, China.
    • J. Gastrointest. Surg. 2017 Jun 1; 21 (6): 936-946.

    ObjectivesTransversus abdominis plane (TAP) block is an analgesic technique. Adding dexmedetomidine can enhance regional anesthesia. This study's aim was to evaluate whether dexmedetomidine prolonged analgesic time of TAP block after gastrectomy.MethodsPatients scheduled for gastrectomy were randomly assigned to receive a TAP block with saline (group S), ropivacaine (group R), or ropivacaine and dexmedetomidine (group RD). Visual analogue scale (VAS) scores, postoperative nausea and vomiting (PONV) scores, sedation scores, tramadol consumption, ropivacaine concentration, and Quality of Recovery Questionnaire 40 (QoR-40) were recorded.ResultsPatients in group R and group RD had lower VAS scores 2, 4, 12, and 24 h after surgery compared with group S (P < 0.05). PONV scores were lower in group R and group RD compared with group S after 2, 12, 24, and 36 h (P < 0.05). Patients in group R and group RD required less tramadol and had better QoR-40 scores than those in group S (P < 0.05). The aforementioned variables and ropivacaine concentrations did not differ between group R and group RD (P > 0.05). Sedation scores were similar between three groups (P > 0.05).ConclusionsTAP block can provide analgesia and improve the quality of recovery. Adding dexmedetomidine does not significantly improve the quality or duration of TAP block.

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