• Neurology · Nov 1994

    Review

    Pharmacokinetics and pharmacodynamics of tizanidine.

    • R C Roberts, N J Part, R Pokorny, C Muir, G C Leslie, and M Emre.
    • Department of Medicine, Dundee University, Scotland, United Kingdom.
    • Neurology. 1994 Nov 1; 44 (11 Suppl 9): S29-31.

    AbstractThe relationship among tizanidine dose, plasma concentration, and antispastic action is linear in nature. Response to a given dose of this agent varies among patients, and determining the appropriate clinical dose requires individual titration.

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