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- Jorge Enrique Machado-Alba, Andrés Gaviria-Mendoza, Manuel Enrique Machado-Duque, and Laura Chica.
- a Grupo de Investigación en Farmacoepidemiología y Farmacovigilancia , Universidad Tecnológica de Pereira - Audifarma S.A. Pereira , Colombia , South America.
- Expert Opin Drug Saf. 2017 Feb 1; 16 (2): 111-112.
AbstractIt is estimated that one-fifth of adult patients are treated with polypharmacy (five or more drugs) and the prevalence of this phenomenon in the elderly is even higher, ranging from 30% to 70%, even reaching 90% in residents of residential aged care facilities. Polypharmacy in the elderly increases the risk of adverse reactions, inappropriate prescriptions, drug interactions, number of hospitalizations, costs, and even death. In a recent systematic review, the authors proposed defining deprescribing as 'the process of withdrawal of inappropriate medication supervised by a health care professional with the goal of managing polypharmacy and improving outcomes'.
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