• Br J Obstet Gynaecol · Jun 1977

    Comparative Study Clinical Trial Controlled Clinical Trial

    Treatment of pregnancy sickness.

    • D Wheatley.
    • Br J Obstet Gynaecol. 1977 Jun 1; 84 (6): 444-7.

    AbstractA double-blind comparison was undertaken between Debendox with 10mg of extra pyridoxine and placebo with 10mg of pyridoxine, in 56 women suffering from nausea and/or vomiting during the first 10 weeks of pregnancy. The results of treatment were assessed on the patient's own dialy records of:the time of nausea, the frequency of nausea, and the severity of nausea, retching and vomiting. There were statistically significant differences in favour of Debendox with extra pyridoxine in respect of the days of nausea all day (P les than 0-02), the severity of nausea (P less than 0-05) and the severity of retching (P less than 0.05).

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