• E Fanucci, G Manenti, A Ursone, N Fusco, I Mylonakou, S D'Urso, and G Simonetti.
• Department of Imaging Diagnostics, Molecular Imaging, Interventional Radiology and Radiotherapy, Policlinico Universitario Tor Vergata, 00133, Rome, Italy. ezio.fanucci@libero.it
• Radiol Med. 2009 Apr 1; 114 (3): 425-36.

PurposeThe authors sought to evaluate indications, technical feasibility and clinical efficacy of computed tomography (CT)-guided pudendal nerve infiltration in patients with chronic anoperineal pain by reviewing the role of the CT technique in their personal experience and in the recent interventional literature.Materials And MethodsTwenty-eight women, mean age 50 years, and with a diagnosis of pudendal neuralgia on the basis of clinical and electromyographic criteria were enrolled in the study. CT-guided pudendal nerve injections were performed during three consecutive sessions held 2 weeks apart. In each session, patients received two percutaneous injections: one in the ischial spine, and the other in the pudendal (Alcock's) canal.ResultsOne patient dropped out of the study after the first session. At clinical assessment, 24h h after treatment, 21/27 patients reported significant pain relief. At follow-up at 3, 6, 9 and 12 months, 24/27 patients reported a>or=20% improvement in the Quality of Life (QOL) index.ConclusionsIn pudendal nerve entrapment, CT-guided perineural injection in the anatomical sites of nerve impingement is a safe and reproducible treatment with a clinical efficacy of 92% at 12 months.

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