• Cerebrovascular diseases · Jan 2001

    Circadian variation of stroke onset in Hong Kong Chinese: a hospital-based study.

    • R T Cheung, W Mak, and K H Chan.
    • Division of Neurology, University Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong. rtcheung@hkucc.hku.hk
    • Cerebrovasc. Dis. 2001 Jan 1; 12 (1): 1-6.

    AbstractCircadian variation of onset of transient ischaemic attack (TIA) or stroke during four 6-hourly periods starting from midnight was studied in Hong Kong Chinese patients admitted to a regional hospital between October 1996 and July 1999. The onset was classifiable into one of the 6-hourly periods in 832 of 905 patients; patients with unclassifiable onset were more likely to have lacunar infarct and less likely to have intracerebral haemorrhage (ICH). There was a significant circadian variation of onset in all strokes and TIA, TIA alone, ischaemic stroke (IS), ICH and different IS subtypes. The risk of onset was greatest between 6 a.m. and noon for IS or TIA, but between noon and 6 p.m. for ICH. There was no difference in the circadian variation between patients with and without prior TIA or stroke. This hospital-based study revealed a significant circadian variation of onset in different types and subtypes of stroke.Copyright 2001 S. Karger AG, Basel

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