• Neurosci. Behav. Physiol. · Mar 2009

    The state of cerebral hemodynamics in conditions of prolonged adaptation to hypercapnic hypoxia.

    • V P Kulikov, A G Bespalov, and N N Yakushev.
    • Federal Agency for Health and Social Development, Altai State Medical University, 40 Lenin Prospekt, Barnaul, 656038, Altai Region, Russia. kulikov@agmu.ru
    • Neurosci. Behav. Physiol. 2009 Mar 1; 39 (3): 269-73.

    AbstractIntermittent hypercapnic hypoxia was accompanied by increases in cerebral vascular resistance, decreases in the reactivity of cerebral vessels to hypercapnia, and increases in the collateral reserve and rate of autoregulation of brain blood flow. These changes were an important component of the mechanism increasing the tolerance of the brain to ischemia in response to training with hypercapnic hypoxia.

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