• Surg Laparosc Endosc · Dec 1996

    Case Reports

    Methemoglobinemia secondary to benzocaine topical anesthetic.

    • E Lee, R Boorse, and M Marcinczyk.
    • Department of Internal Medicine, Lehigh Valley Hospital, Allentown, Pennsylvania 18105-1556, USA.
    • Surg Laparosc Endosc. 1996 Dec 1; 6 (6): 492-3.

    AbstractAn 80-year-old white woman with a history of hypertension presented to the Emergency Department with bright red bleeding from the rectum. She was treated with 5 mg of midazolam and benzocaine topical anesthetic spray prior to undergoing colonoscopy and esophageal gastroduodenoscopy. Thirty minutes after endoscopy, the patient became cyanotic and dyspneic; she was suffering from methemoglobinemia, a rare complication secondary to the use of benzocaine topical anesthetic spray. After i.v. administration of methylene blue, 120 mg (2 mg/kg) in 100 cc of normal saline solution, the cyanosis and dyspnea resolved.

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