• Leonie E van Rheenen-Flach, Sonja Zweegman, Fleur Boersma, Joris E Lenglet, Jos W R Twisk, and Antoinette C Bolte.
• Department of Obstetrics and Gynecology, VU University Medical Center, Amsterdam, The Netherlands. leonie_flach@hotmail.com
• Aust N Z J Obstet Gynaecol. 2013 Feb 1; 53 (1): 32-6.

BackgroundRotation thromboelastometry (ROTEM) is an easy, fast and complete method of measuring coagulation.AimsOur goal was to obtain longitudinal values on ROTEM in uncomplicated pregnancies and in the puerperium.Materials And MethodsHealthy women, who visited our outpatient clinic for antenatal checks and who accomplished an uncomplicated pregnancy were tested three times during pregnancy and one time postpartum. Intrinsic and extrinsic pathway tests were carried out.ResultsIn total, 62 women were analysed, and 298 measurements were taken. With increasing gestational age, there are significant changes towards hypercoagulability.ConclusionThis study provides a better knowledge about physiological changes in ROTEM measurements during pregnancy. These normative data may serve as assistance for future studies and interventions.© 2012 The Authors ANZJOG © 2012 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists.

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