• JAMA · Aug 2018

    Probiotics to Prevent Clostridium difficile Infection in Patients Receiving Antibiotics.

    • Joshua Z Goldenberg, Dominik Mertz, and Bradley C Johnston.
    • Bastyr University Research Institute, Kenmore, Washington.
    • JAMA. 2018 Aug 7; 320 (5): 499-500.

    Clinical QuestionIn adults and children prescribed antibiotics, is co-administration of a probiotic associated with a lower risk of symptomatic Clostridium difficile infection without an increase in adverse events?Bottom LineModerate-quality evidence suggests that probiotics are associated with a lower risk of C difficile infection and very low-quality evidence suggests that probiotics are associated with fewer adverse events vs placebo or no treatment.

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