• Geraldo O Silva-Junior, Bruna L Picciani, Raphael C Costa, Saulo M Barbosa, Marcelo G Silvares, Ramiro B Souza, Marília H Cantisano, and Fabio R Pires.
• Department of Stomatology, School of Dentistry, State University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
• J Oral Sci. 2013 Mar 1; 55 (1): 85-8.

AbstractOral angiolipomas are exceedingly rare and little is known about their morphological and etiological features. Here, we report two cases of oral angiolipoma and discuss their clinicopathological and immunohistochemical features, focusing on endothelial markers. Both lesions presented mature adipocytes interspersed by small blood vessels containing fibrin thrombi. Immunohistochemical analysis showed numerous mast cells and expression of CD34, vascular endothelial growth factor, intercellular adhesion molecule-1, interferon-γ and interleukin 6 in most endothelial and stromal cells. Mast cell-endothelial cell interaction may be responsible for the reactive or neoplastic origin of the vascular proliferation of these entities.

39 keywords...

hide…