• Recenti Prog Med · Jan 1990

    Case Reports

    [Disulfiram-like effect of cefonicid: first observation].

    • G Marcon, A Spolaor, M Scevola, M Zolli, and G B Carlassara.
    • Divisione di Medicina generale, ULSS 17 Veneto, Ospedale, Mirano.
    • Recenti Prog Med. 1990 Jan 1; 81 (1): 47-8.

    AbstractThe disulfiram-like reaction is linked to the assumption of ethyl alcohol during therapy with the cephalosporin latamoxef, cefamandole and cefoperazone. The reaction is commonly ascribed to the methyl-thiotetrazole group, resembling part of the disulfiram molecule. We describe the case of a patient who experienced on two different occasions a disulfiram-like effect during therapy with cefonicid. This cephalosporin contains the methylsulphothiotetrazole group in place of the methylthiotetrazole group. Our observation is the first related to cefonicid.

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