• Anesthesia and analgesia · Jun 2019

    Randomized Controlled Trial

    Effect of Intravenous Dexamethasone on the Regression of Isobaric Bupivacaine Spinal Anesthesia: A Randomized Controlled Trial.

    Intravenous dexamethasone does not effect duration of isobaric bupivacaine spinal block.

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    • Juliane Guay, Stephan R Williams, Florian Robin, and Monique Ruel.
    • From the Département d'anesthésiologie, Centre hospitalier de l'Université de Montréal, Hôpital Notre-Dame, Montréal, Québec, Canada.
    • Anesth. Analg. 2019 Jun 1; 128 (6): e100e103e100-e103.

    AbstractThe effect of intravenous dexamethasone on the regression of sensory and motor block after isobaric bupivacaine spinal anesthesia is unknown. We conducted a prospective, double-blind, randomized controlled trial on 60 patients who received intravenously either placebo (group P) or 8-mg dexamethasone (group D) during the intrathecal injection of 12-mg isobaric bupivacaine 0.5%. Primary outcome was the time from bupivacaine injection to regression of 2 dermatomes in relation to the highest dermatome blocked by the spinal local anesthetic. Time to 2-dermatome regression was 85 minutes (74-96 minutes) in group P versus 87 minutes (76-98 minutes) in group D (P = .79).

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    Intravenous dexamethasone does not effect duration of isobaric bupivacaine spinal block.

    Daniel Jolley  Daniel Jolley
     
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